Product Name: AZ 10606120 dihydrochloride
Subtitle: Potent P2X7 receptor antagonist
Biological Activity: Biological Activity of AZ 10606120 dihydrochloridePotent P2X7 receptor antagonist (KD values are 1.4 and 19 nM at human and rat P2X7 receptors respectively). Binds in a positive cooperative manner to sites distinct from, but coupled to, the ATP binding si
SMLES:
CAS NO: 548783-71-7
Standard In CHIKey: Checkpoint Kinase Chk) inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C25H34N4O2.2HCl
M.Wt: 495.48
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/272/2/766
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 25 mM in water and to 100 mM in DMSO
Storage: Desiccate at RT
Purity: >98%
Chemical Name: N-[2-[[2-[(2-Hydroxyethyl)amino]ethyl]amino]-5-quinolinyl]-2-tricyclo[3.3.1.13,7]dec-1-ylacetamide dihydrochloride