Product Name: LY2090314
Subtitle: Potent GSK-3 inhibitor
Biological Activity: Biological Activity of LY2090314Description LY2090314 is a potent inhibitor of glycogen synthase kinase-3 (GSK-3) with IC50 value of 1.5 nM and 0.9 nM for GSK-3α and GSK-3β, respectively. Targets GSK-3α GSK-3β IC50 1.5 nM 0.9 nM
SMLES: FC1=C([H])C2=C(C(C(C(C(N([H])C3=O)=O)=C3C4=C([H])N=C5N4C([H])=C([H])C([H])=C5[H])=C6[H])=C1[H])N6C([H])([H])C([H])([H])N(C(N7C([H])([H])C([H])([H])C([H])([H])C([H])([H])C7([H])[H])=O)C2([H])[H]
CAS NO: 1446182-94-0
Standard In CHIKey: Aurora Kinase inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C28H25FN6O3
M.Wt: 512.53
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/257/2/555
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO
Storage:
Purity: >98%
Chemical Name: 3-(9-fluoro-2-(piperidine-1-carbonyl)-1,2,3,4-tetrahydro-[1,4]diazepino[6,7,1-hi]indol-7-yl)-4-(imidazo[1,2-a]pyridin-3-yl)-1H-pyrrole-2,5-dione