Product Name: MK-2206 dihydrochloride
Subtitle: Akt1/2/3 inhibitor
Biological Activity: Biological Activity of MK-2206 dihydrochlorideDescription MK-2206 2HCl is a highly selective inhibitor of Akt1/2/3 with IC50 of 8 nM/12 nM/65 nM, respectively. Targets Akt1 Akt2 Akt3 IC50 8 nM 12 nM 65 nM
SMLES: C1CC(C1)(C2=CC=C(C=C2)C3=C(C=C4C(=N3)C=CN5C4=NNC5=O)C6=CC=CC=C6)N.Cl.Cl
CAS NO: 670220-88-9
Standard In CHIKey: Apoptosis inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C25H21N5O.2HCl
M.Wt: 480.39
General Tips: for obtaining a higher concentration: Please warm the tube at 37 °C for 10 minutes and/or shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.PubMed ID:http://jpet.aspetjournals.org/content/257/1/472
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-2H-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3-one;dihydrochloride