Product Name: PIT 1
Subtitle:
Biological Activity: Biological Activity of PIT 1Selective PIP3 antagonist. Blocks the binding of PIP3 to the pleckstrin homology (PH) domain of Akt (IC50 = 31.03 μM). Inhibits cancer cell survival and induces apoptosis by inhibition of PIP3-dependent PI 3-kinase/Akt sig
SMLES: ClC1=CC([N+]([O-])=O)=CC(NC(NC(C2=CC=CC=C2)=O)=S)=C1O
CAS NO: 13382-86-0
Standard In CHIKey: CFTR inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C14H10ClN3O4S
M.Wt: 351.76
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/271/1/567
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 75 mM in DMSO
Storage: Store at +4℃
Purity: >98%
Chemical Name: N-[[(3-Chloro-2-hydroxy-5-nitrophenyl)amino]thioxomethyl]benzamide