Product Name: RP 67580
Subtitle:
Biological Activity: Biological Activity of RP 67580Potent and selective tachykinin NK1 receptor antagonist (Ki values are 2.9 nM and > 10 μM for rat NK1, and rat NK2 and NK3 receptors respectively). Displays higher affinity at rat and mouse than human receptors. Antino
SMLES: O=C1[C@@H]2[C@@H](CN(C(CC3=CC=CC=C3OC)=N)C2)C(C4=CC=CC=C4)(C5=CC=CC=C5)CC1
CAS NO: 18683-91-5
Standard In CHIKey: VWBOQFANCXZMAU-LOSJGSFVSA-NRas inhibitors
Standard InChI: InChI=1S/C29H30N2O2/c1-33-27-15-9-8-10-21(27)18-28(30)31-19-24-25(20-31)29(17-16-26(24)32,22-11-4-2-5-12-22)23-13-6-3-7-14-23/h2-15,24-25,30H,16-20H2,1H3/t24-,25+/m0/s1
Typrof Compound:
Appearance:
Formula: C29H30N2O2
M.Wt: 438.57
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/270/1/55
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in ethanol and to 50 mM in DMSO
Storage: Store at -20℃
Purity: >98%
Chemical Name: (3aR,7aR)-Octahydro-2-[1-imino-2-(2-methoxyphenyl)ethyl]-7,7-diphenyl-4H-isoindol