Product Name: LFM-A13Subtitle: BTK-specific tyrosine kinase inhibitorBiological Activity: SMLES: C/C(O)=C(/C(O)=N/C1=C(Br)C=CC(Br)=C1)C#NCAS NO: 287194-40-5Standard In CHIKey: Interleukin Related inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C11H8Br2N2O2M.Wt: 360General Tips: For obtaining a higher solubility…
Product Name: ONO-4059Subtitle: Highly potent and selective oral Btk inhibitorBiological Activity: SMLES: NC1=C(N(C(N23CN(C(C=C)=O)CCC3)=O)C(C=C4)=CC=C4OC5=CC=CC=C5)C2=NC=N1CAS NO: 941678-49-5Standard In CHIKey: IFNAR inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C25H24N6O3M.Wt: 456.5General Tips: For obtaining a…
Product Name: FG2216Subtitle: HIF-prolyl hydroxylase inhibitorBiological Activity: SMLES: ClC1=NC(/C(O)=N/CC(O)=O)=C(O)C2=CC=CC=C21CAS NO: 1419949-20-4Standard In CHIKey: FLAP inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C12H9ClN2O4M.Wt: 280.66General Tips: For obtaining a higher solubility , please…
Product Name: Leukadherin 1Subtitle: CD11b/CD18 activatorBiological Activity: Biological Activity of Leukadherin 1Allosteric activator of CD11b/CD18. Increases CD11b/CD18-dependent cell adhesion to fibrinogen (EC50 = 4 μM). Decreases leukocyte motility and transendothelial…
Product Name: P11Subtitle: Biological Activity: Biological Activity of P11Potent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.SMLES: N/ACAS NO: 108212-75-5Standard…
Product Name: LDV FITCSubtitle: Biological Activity: Biological Activity of LDV FITCFluorescent ligand that binds to the α4β1 integrin (VLA-4) with high affinity (Kd values are 0.3 nM and 12 nM…
Product Name: TC-I 15Subtitle: Biological Activity: Biological Activity of TC-I 15Potent α2β1 integrin inhibitor (IC50 values for the inhibition of human platelet adhesion to type I collagen are 12 and…
Product Name: TCS 2314Subtitle: Biological Activity: Biological Activity of TCS 2314Integrin very late antigen-4 (VLA-4; α4β1) antagonist (IC50 = 4.4 nM). Blocks the activation of inflammatory cells.SMLES: N/ACAS NO: 1255580-76-7Standard…
Product Name: Echistatin, α1 isoformSubtitle: Biological Activity: Biological Activity of Echistatin, α1 isoformPotent irreversible αVβ3 integrin antagonist (Ki = 0.27 nM). Disrupts attachment of osteoclasts to bone and inhibits bone…
Product Name: CWHM-12Subtitle: Biological Activity: SMLES: CC(C)(C)C1=CC(=CC(=C1)C(CN(C(=O)CN)C(=O)C2=CC(=CC(=C2)O)NC3=NCC(CN3)O)C(=O)O)BrCAS NO: 894787-30-5Standard In CHIKey: Somatostatin Receptor inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C26H32BrN5O6M.Wt: 590.47General Tips: For obtaining a higher solubility , please warm…