Name : Human EGFL7 Protein

Product Source :
Recombinant Human EGFL7 Protein is expressed from E.coli with His tag at the N-Terminus. It contains Tyr24-Ser273.[Accession | Q9UHF1]

Molecular Weight :
The protein has a predicted MW of 28.4 kDa same as Tris-Bis PAGE result.

Endotoxin Level :
Less than 1EU per ug by the LAL method.

Purity :
> 95% as determined by Tris-Bis PAGE

Formulation :
Supplied as 0.22μm filtered solution in 4mM HCl (pH 3.0).

Reconstitution :

Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Product Concentration :
Tris-Bis PAGE Human EGFL7 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. ELISA Data Immobilized Human EGFL7, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Anti-EGFL7 Antibody, hFc Tag with the EC50 of 17.5ng/ml determined by ELISA.

Background :
Epidermal growth factor-like domain-containing protein 7 (EGFL7), a member of the epidermal growth factor (EGF)-like protein family, is a potent angiogenic factor expressed in many different cell types. EGFL7 plays a vital role in controlling vascular angiogenesis during embryogenesis, organogenesis, and maintaining skeletal homeostasis.

Synonyms :
EGF-like protein 7; NOTCH4-like protein; VE-statin; NEU1; ZNEU1; EGFL7; MEGF7; MGC111117; RP11-251M1.2

References & Citations :
(1) Hong G, Kuek V, Shi J, Zhou L, Han X, He W, Tickner J, Qiu H, Wei Q, Xu J. EGFL7: Master regulator of cancer pathogenesis, angiogenesis and an emerging mediator of bone homeostasis. J Cell Physiol. 2018 Nov;233(11):8526-8537. doi: 10.1002/jcp.26792. Epub 2018 Jun 19. PMID: 29923200.

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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