Product Name: B-Raf inhibitorSubtitle: A B-Raf inhibitorBiological Activity: SMLES: CCN1CCN(CC1)Cc2ccc(cc2C(F)(F)F)NC(=O)c3ccc(c(c3)Oc4c5cc(c5ncn4)C)CCAS NO: 918504-65-1Standard In CHIKey: Quinones inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C29H31F3N6O2M.Wt: 552.59General Tips: For obtaining a higher solubility ,…
Product Name: BRAF inhibitorSubtitle: Potent B-raf inhibitorBiological Activity: SMLES: CC(C)S(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)C4=CN=CC=C4)FCAS NO: 1028486-01-2Standard In CHIKey: Phenylpropanoids inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C22H18F2N4O3SM.Wt: 456.47General Tips: For obtaining a higher solubility ,…
Product Name: AS 602801Subtitle: Jun Kinase InhibitorBiological Activity: SMLES: CAS NO: 1195765-45-7Standard In CHIKey: Saccharides and Glycosides inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C25H23N5O2SM.Wt: 457.55General Tips: For obtaining a higher…
Product Name: Trametinib (GSK1120212)Subtitle: MEK1 and MEK2 inhibitor, potent and selectiveBiological Activity: Biological Activity of Trametinib (GSK1120212)Description Trametinib (GSK1120212) is a highly specific and potent inhibitor of MEK1/2 with IC50…
Product Name: PLX-4720Subtitle: BRAF kinase inhibitorBiological Activity: Biological Activity of PLX-4720Description PLX4720 is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM, equally potent to c-Raf-1(Y340D and…
Product Name: PD0325901Subtitle: MEK inhibitorBiological Activity: Biological Activity of PD0325901Potent MEK1 and MEK2 inhibitor. Inhibits MEK activity in mouse colon 26 cells (IC50 = 0.33 nM). Inhibits the growth of…
Product Name: Vemurafenib (PLX4032, RG7204)Subtitle: BRAF kinase inhibitorBiological Activity: Biological Activity of Vemurafenib (PLX4032, RG7204)Description Vemurafenib (PLX4032, RG7204) is a novel and potent inhibitor of B-RafV600E with IC50 of 31…
Product Name: MEK162 (ARRY-162, ARRY-438162)Subtitle: MEK1/2 inhibitor,potent and selectiveBiological Activity: Biological Activity of MEK162 (ARRY-162, ARRY-438162)Description MEK162 is a potent inhibitor of MEK1/2 with IC50 value of 12 nM. Targets…
Product Name: SL-327Subtitle: Selective MEK1/2 inhibitorBiological Activity: Biological Activity of SL-327Selective inhibitor of MEK1 and MEK2 (IC50 values are 0.18 and 0.22 μM respectively); blocks hippocampal LTP in vitro. Brain…
Product Name: PD184352 (CI-1040)Subtitle: Selective MEK inhibitorBiological Activity: Biological Activity of PD184352 (CI-1040)Selective MEK inhibitor (Ki = 300 nM in vitro). Suppresses FGF-mediated angiogenesis in vivo and decreases VEGF expression.…