Product Name: A 331440 dihydrochloride
Subtitle: H3 receptor antagonist,non-imidazole,high affinity
Biological Activity: Biological Activity of A 331440 dihydrochlorideHigh affinity histamine H3 receptor antagonist (Ki values are 21.7 and 22.7 nM for rat and human H3 receptors, respectively). Exhibits selectivity for human H3 over H1, H2 and H4 receptors (Ki values are 2940
SMLES:
CAS NO: 434-05-9
Standard In CHIKey: GPCR19 inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C22H27N3O.2HCl
M.Wt: 422.39
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/270/3/979
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in water and to 20 mM in DMSO
Storage: Desiccate at RT
Purity: >98%
Chemical Name: 4'-[3-[(3R)-3-(Dimethylamino)-1-pyrrolidinyl]propoxy]-[1,1'-biphenyl]-4-carbonitrile dihydrochloride