Product Name: A 366
Subtitle: G9a/GLP histone lysine methyltransferase inhibitor
Biological Activity: Biological Activity of A 366Potent and selective G9a/GLP histone lysine methyltransferase inhibitor (IC50 = 3.3 nM). Exhibits >1000-fold selectivity for G9a/GLP over 21 other methyltransferases. Decreases levels of lysine 9 dimethylation on histone H
SMLES:
CAS NO: 179248-59-0
Standard In CHIKey: MAPK_Compound_Library inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C19H27N3O2
M.Wt: 329.44
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/261/3/936
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in 1eq. HCl and to 100 mM in DMSO
Storage: Store at -20℃
Purity: >98%
Chemical Name: 5'-Methoxy-6'-[3-(1-pyrrolidinyl)propoxy]spiro[cyclobutane-1,3'-[3H]indol]-2'-amine