Product Name: AM 281
Subtitle: CB1 antagonist
Biological Activity: Biological Activity of AM 281Potent, selective CB1 cannabinoid receptor antagonist/inverse agonist (Ki values are 12 and 4200 nM for CB1 and CB2 receptors respectively). Increases locomotor activity following systemic administration in vivo. Analog of SR1
SMLES:
CAS NO: 76822-21-4
Standard In CHIKey: JAK_STAT Signaling inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C21H19Cl2IN4O2
M.Wt: 557.22
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/264/3/1474
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 75 mM in DMSO with gentle warming
Storage: Desiccate at +4℃
Purity: >98%
Chemical Name: 1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl-1H-pyrazole-3-carboxamide