Product Name: AMG-458
Subtitle: Potent c-Met inhibitor
Biological Activity: Biological Activity of AMG-458Description AMG 458 is a potent inhibitor of c-Met with a Ki value of 1.2 nM. Targets c-Met (H1094R) c-Met (V1092I) c-Met (Human) c-Met (Mouse) c-Met (D1228H) IC50 0.5 nM(Ki) 1.1 nM(Ki) 1.2 nM(Ki) 2.0 nM
SMLES:
CAS NO: 247257-48-3
Standard In CHIKey: Opioid Receptor inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C30H29N5O5
M.Wt: 539.58
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/274/3/1507
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility:
Storage:
Purity: >98%
Chemical Name: