Product Name: CP 465022 hydrochloride
Subtitle: AMPA receptor antagonist, non-competitive and selective
Biological Activity: Biological Activity of CP 465022 hydrochlorideSelective, non-competitive AMPA antagonist (IC50 = 25 nM in rat cortical neurons) that displays potent anticonvulsant activity. Also significantly blocks the persistent component of Nav1.6 channel activity. Br
SMLES: ClC1=CC=CC=C1N(C(/C=C/C2=NC(CN(CC)CC)=CC=C2)=NC3=C4C=C(F)C=C3)C4=O.[H]Cl
CAS NO: 113559-13-0
Standard In CHIKey: Inhibitor_Kit inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C26H24ClFN4O.HCl
M.Wt: 499.41
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/274/1/481
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 10 mM in water and to 100 mM in DMSO
Storage: Desiccate at RT
Purity: >98%
Chemical Name: 3-(2-Chlorophenyl)-2-[2-[6-[(diethylamino)methyl]-2-pyridinyl]ethenyl]-6-fluoro-4(3H)-quinazolinone hydrochloride