Product Name: Cilastatin sodium
Subtitle:
Biological Activity: Biological Activity of Cilastatin sodiumDipeptidase inhibitor (LTDase, leukotriene D4 hydrolase, dehydropeptidase I) that displays a Ki value of 0.11 μM. Inhibits metabolism of LTD4 to LTE4 and the hydrolysis of β-lactam antibiotics. Nephroprotective;
SMLES: O=C([C@@H]1C(C)(C)C1)N/C(C([O-])=O)=CCCCCSC[C@@H](C(O)=O)N.[Na+]
CAS NO: 58546-56-8
Standard In CHIKey: QXPBTTUOVWMPJN-VQAYNFQASA-MBcr-Abl inhibitors
Standard InChI: InChI=1S/C16H26N2O5S.Na/c1-16(2)8-10(16)13(19)18-12(15(22)23)6-4-3-5-7-24-9-11(17)14(20)21;/h6,10-11H,3-5,7-9,17H2,1-2H3,(H,18,19)(H,20,21)(H,22,23);/q;+1/p-1/b12-6-;/t10-,11-;/m1./s1
Typrof Compound:
Appearance:
Formula: C16H25N2NaO5S
M.Wt: 380.43
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/271/3/1399
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in water and to 10 mM in DMSO
Storage: Desiccate at -20℃
Purity: >98%
Chemical Name: (2Z)-7-[[(2R)-2-Amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic acid sodium salt