Product Name: Cromakalim
Subtitle:
Biological Activity: Biological Activity of CromakalimPrototypical Kir6 (KATP) channel opener. Relaxes rabbit isolated portal vein with an IC50 value of 21 nM . Potent, orally active and hypotensive in vivo.
SMLES: O[C@H](C(C)(C)OC1=C2C=C(C#N)C=C1)[C@@H]2N3CCCC3=O
CAS NO: 17391-18-3
Standard In CHIKey: TVZCRIROJQEVOT-UHFFFAOYSA-NProcollagen C Proteinase inhibitors
Standard InChI: InChI=1S/C16H18N2O3/c1-16(2)15(20)14(18-7-3-4-13(18)19)11-8-10(9-17)5-6-12(11)21-16/h5-6,8,14-15,20H,3-4,7H2,1-2H3
Typrof Compound:
Appearance:
Formula: C16H18N2O3
M.Wt: 286.33
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/273/3/1032
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 20 mM in DMSO
Storage: Store at RT
Purity: >98%
Chemical Name: trans-3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-2H-1-benzopyran-6-carbonitrile