Product Name: E-4031 dihydrochloride
Subtitle:
Biological Activity: Biological Activity of E-4031 dihydrochlorideSelective blocker of KV11.1 (hERG) channels; inhibits the rapid delayed-rectifier K+ current (IKr). Reversibly prolongs action potential duration in guinea pig papillary muscle and isolated ventricular myocytes
SMLES: O=C(C(C=C1)=CC=C1NS(=O)(C)=O)C2CCN(CCC3=NC(C)=CC=C3)CC2.Cl.Cl
CAS NO: 7181-73-9
Standard In CHIKey: ZQBNWMFBOSOOLX-UHFFFAOYSA-NBtk inhibitors
Standard InChI: InChI=1S/C21H27N3O3S.2ClH/c1-16-4-3-5-19(22-16)12-15-24-13-10-18(11-14-24)21(25)17-6-8-20(9-7-17)23-28(2,26)27;;/h3-9,18,23H,10-15H2,1-2H3;2*1H
Typrof Compound:
Appearance:
Formula: C21H27N3O3S.2HCl
M.Wt: 474.44
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/273/3/1390
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in water and to 50 mM in DMSO
Storage: Desiccate at RT
Purity: >98%
Chemical Name: N-[4-[[1-[2-(6-Methyl-2-pyridinyl)ethyl]-4-piperidinyl]carbonyl]phenyl]methanesulfonamide dihydrochloride