Product Name: EPZ004777 HCl
Subtitle: DOT1L inhibitor,potent and selective
Biological Activity: Biological Activity of EPZ004777 HClDescription EPZ004777 HCl is a potent, selective inhibitor of DOT1L with an IC50 value of 0.4 nM. Targets DOT1L IC50 0.4 nM
SMLES: CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)CC2C(C(C(O2)N3C=CC4=C3N=CN=C4N)O)O.Cl
CAS NO: 1105698-15-4
Standard In CHIKey: Androgen Receptor inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C28H41N7O4.HCl
M.Wt: 576.13
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/261/3/1195
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO
Storage:
Purity: >98%
Chemical Name: 1-[3-[[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxyoxolan-2-yl]methyl-propan-2-ylamino]propyl]-3-(4-tert-butylphenyl)urea;hydrochloride