Product Name: Entinostat (MS-275,SNDX-275)
Subtitle: HDAC1 and HDAC3 inhibitor
Biological Activity: Biological Activity of Entinostat (MS-275,SNDX-275)Description Entinostat (MS-275) is a strong inhibitor of HDAC1 and HDAC3 with IC50 of 0.51 μM and 1.7 μM, compared with HDACs 4, 6, 8, and 10. Targets HDAC1 HDAC3 IC50 0.51 μM 1
SMLES: C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC(=O)OCC3=CN=CC=C3
CAS NO: 122795-43-1
Standard In CHIKey: INVTYAOGFAGBOE-UHFFFAOYSA-NMembrane_Transporter/Ion_Channel_Compound_Library inhibitors
Standard InChI: InChI=1S/C21H20N4O3/c22-18-5-1-2-6-19(18)25-20(26)17-9-7-15(8-10-17)13-24-21(27)28-14-16-4-3-11-23-12-16/h1-12H,13-14,22H2,(H,24,27)(H,25,26)
Typrof Compound:
Appearance:
Formula: C21H20N4O3
M.Wt: 376.4
General Tips: for obtaining a higher concentration: Please warm the tube at 37 °C for 10 minutes and/or shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.PubMed ID:http://jpet.aspetjournals.org/content/252/3/1202
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: pyridin-3-ylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate