Product Name: Flurizan
Subtitle: NSAID,inhibits γ-secretase activity
Biological Activity: Biological Activity of FlurizanNonsteroidal anti-inflammatory drug (NSAID) that inhibits γ-secretase activity. Selectively lowers Aβ42 levels in human neuroglioma cells; displays no effect on Aβ40 levels at a concentration of 100 μM.
SMLES: CC(C1=CC(=C(C=C1)C2=CC=CC=C2)F)C(=O)O
CAS NO: 269718-84-5
Standard In CHIKey: SYTBZMRGLBWNTM-SNVBAGLBSA-NSGLT inhibitors
Standard InChI: InChI=1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)/t10-/m1/s1
Typrof Compound:
Appearance:
Formula: C15H13FO2
M.Wt: 244.26
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/271/2/1086
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage: Store at RT
Purity: >98%
Chemical Name: (R)-2-Fluoro-α-methyl[1,1-biphenyl]-4-acetic acid