Product Name: Fumitremorgin C
Subtitle:
Biological Activity: Biological Activity of Fumitremorgin CChemosensitizing agent; selectively reverses BCRP-mediated multidrug resistance to mitoxantrone, doxorubicin and topotecan in transfected MCF-7 cells. Does not reverse resistance in P-gp- or MRP-positive cells. Analog
SMLES: O=C([C@H]1N(C2=O)CCC1)N([C@H]3/C=C(C)C)[C@H]2CC4=C3NC5=C4C=CC(OC)=C5
CAS NO: 479-41-4
Standard In CHIKey: DBEYVIGIPJSTOR-FHWLQOOXSA-NNF-κB_Signaling_Compound_Library inhibitors
Standard InChI: InChI=1S/C22H25N3O3/c1-12(2)9-18-20-15(14-7-6-13(28-3)10-16(14)23-20)11-19-21(26)24-8-4-5-17(24)22(27)25(18)19/h6-7,9-10,17-19,23H,4-5,8,11H2,1-3H3/t17-,18-,19-/m0/s1
Typrof Compound:
Appearance:
Formula: C22H25N3O3
M.Wt: 379.45
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/274/1/444
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 10 mM in DMSO
Storage: Store at +4℃
Purity: >98%
Chemical Name: (5aS,12S,14aS)-1,2,3,5a,6,11,12,14a-Octahydro-9-methoxy-12-(2-methyl-1-propen-1-yl)-5H,14H-pyrrolo[1,2:4,5]pyrazino[1,2:1,6]pyrido[3,4-b]indole-5,14-dione