Product Name: GANT61
Subtitle: GLI antagonist
Biological Activity: Biological Activity of GANT61GLI antagonist that inhibits GLI1 and GLI2-induced transcription (IC50 ~ 5 μM). Inhibits the hedgehog (Hh) signaling pathway downstream of SMO and SUFU causing GLI1 nuclear accumulation. Displays antiproliferative and ant
SMLES: CN(C)c1ccccc1CN2CCCN(C2c3ccncc3)Cc4ccccc4N(C)C
CAS NO: 1235034-55-5
Standard In CHIKey: Neprilysin inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C27H35N5
M.Wt: 429.6
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/259/2/751
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 50 mM in DMSO and to 100 mM in ethanol
Storage: Store at -20℃
Purity: >98%
Chemical Name: 2,2-[[Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethylbenzenamine