Product Name: GDC-0032
Subtitle: PI3Kα inhibitor
Biological Activity: Biological Activity of GDC-0032Description GDC-0032 is a potent, next-generation inhibitor of β isoform-sparing PI3K with IC50 values of 0.29 nM/0.12 nM/0.97nM for PI3Kα/δ/γ, respectively. Targets PI3Kδ PI3Kα PI3Kγ IC50 0.12 nM 0.29
SMLES: CC1=NN(C(=N1)C2=CN3CCOC4=C(C3=N2)C=CC(=C4)C5=CN(N=C5)C(C)(C)C(=O)N)C(C)C
CAS NO: 1445379-92-9
Standard In CHIKey: Cannabinoid Receptor inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C24H28N8O2
M.Wt: 460.53
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/257/3/1045
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO
Storage:
Purity: >98%
Chemical Name: 2-methyl-2-[4-[2-(5-methyl-2-propan-2-yl-1,2,4-triazol-3-yl)-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl]pyrazol-1-yl]propanamide