Product Name: GNF-5837
Subtitle: Pan-Trk inhibitor
Biological Activity: Biological Activity of GNF-5837Potent pan-Trk inhibitor. Displays antiproliferative effects in cellular Ba/F3 assays (IC50 values are 7, 9 and 11 nM for cells containing the fusion proteins Tel-TrkC, Tel-TrkB and Tel-TrkA, respectively). Exhibits selectiv
SMLES: O=C(NC1=CC(C(F)(F)F)=CC=C1F)NC2=CC=C(C)C(NC3=CC(NC/4=O)=C(C=C3)C4=CC5=CC=CN5)=C2
CAS NO: 1428-67-7
Standard In CHIKey: GPR84 inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C28H21F4N5O2
M.Wt: 535.49
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/274/3/1404
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 10 mM in ethanol
Storage: Store at +4℃
Purity: >98%
Chemical Name: N-[3-[[2,3-Dihydro-2-oxo-3-(1H-pyrrol-2-ylmethylene)-1H-indol-6-yl]amino]-4-methylphenyl]-N-[2-fluoro-5-(trifluoromethyl)phenyl]urea