Product Name: GR 159897
Subtitle:
Biological Activity: Biological Activity of GR 159897A potent, selective, non-peptide, orally active neurokinin NK2 receptor antagonist. Competes for binding of [3H]GR100679 to hNK2-transfected CHO cells with a pKi of 9.5. Inhibits NK2 receptor-mediated contraction of guinea
SMLES: FC1=CC=C2NC=C(C2=C1)CCN3CCC(CC3)(CS(C4=CC=CC=C4)=O)OC
CAS NO: 821768-06-3
Standard In CHIKey: BCRP inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C23H27FN2O2S
M.Wt: 414.54
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/265/1/178
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 50 mM in DMSO and to 10 mM in ethanol
Storage: Desiccate at -20℃
Purity: >98%
Chemical Name: 5-Fluoro-3-[2-[4-methoxy-4-[[(R)-phenylsulphinyl]methyl]-1-piperidinyl]ethyl]-1H-indole