Product Name: GSK 2193874
Subtitle:
Biological Activity: Biological Activity of GSK 2193874Potent and selective TRPV4 antagonist (IC50 values are 2 and 40 nM for rat and human receptors, respectively); inhibits Ca2+ influx through TRPV4 channels. Prevents and reverses pulmonary edema after myocardial infarction
SMLES: N/A
CAS NO:
Standard In CHIKey: Epigenetic Reader Domain inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C37H38BrF3N4O
M.Wt: 691.62
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/274/3/1129
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 20 mM in 1eq. HCl and to 50 mM in DMSO
Storage: Store at +4℃
Purity: >98%
Chemical Name: 3-([1,4'-Bipiperidin]-1'-ylmethyl)-7-bromo-N-(1-phenylcyclopropyl)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxamide