Product Name: GSK461364
Subtitle: Plk1 inhibitor
Biological Activity: Biological Activity of GSK461364Description GSK461364 is a inhibitor of Plk1 with a Ki value of 2.2 nM. Targets PLK1 IC50 2.2 nM(Ki)
SMLES: CC(C1=CC=CC=C1C(F)(F)F)OC2=C(SC(=C2)N3C=NC4=C3C=C(C=C4)CN5CCN(CC5)C)C(=O)N
CAS NO: 1256580-46-7
Standard In CHIKey: MMP inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C27H28F3N5O2S
M.Wt: 543.6
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/252/1/339
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 5-[6-[(4-methylpiperazin-1-yl)methyl]benzimidazol-1-yl]-3-[(1R)-1-[2-(trifluoromethyl)phenyl]ethoxy]thiophene-2-carboxamide