Product Name: Ganaxolone
Subtitle:
Biological Activity: Biological Activity of GanaxolonePotent positive allosteric modulator of GABAA receptors. Enhances GABA-evoked chloride currents in Xenopus oocytes expressing GABAA receptors (EC50 values are 94, 122 and 213 nM for α2β1γ2L, α3β1γ2L
SMLES: O[C@@]1(C)C[C@H]2[C@@](CC1)(C)[C@@H]3[C@@H](CC2)[C@H]4[C@]([C@@H](C(C)=O)CC4)(C)CC3
CAS NO: 1651890-44-6
Standard In CHIKey: PGTVWKLGGCQMBR-XYZZJYPZSA-NCancer inhibitors
Standard InChI: InChI=1S/C22H36O2/c1-14(23)17-7-8-18-16-6-5-15-13-20(2,24)11-12-21(15,3)19(16)9-10-22(17,18)4/h15-19,24H,5-13H2,1-4H3/t15-,16?,17+,18?,19?,20+,21-,22+/m0/s1
Typrof Compound:
Appearance:
Formula: C22H36O2
M.Wt: 332.53
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/274/1/242
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 10 mM in DMSO with gentle warming and to 20 mM in ethanol
Storage: Store at +4℃
Purity: >98%
Chemical Name: (3α,5α)-3-Hydroxy-3-methyl-pregnan-20-one