Product Name: HBX 41108
Subtitle:
Biological Activity: Biological Activity of HBX 41108Inhibitor of ubiquitin-specific protease (USP) 7 activity (IC50 = 424 nM). Displays uncompetitive inhibition. Also inhibits USP7-mediated p53 deubiquitination (IC50 = 0.8 μM). Stabilizes p53 and inhibits cancer cell gr
SMLES: ClC1=CC=C(C2=NC(C#N)=C(C#N)N=C2C3=O)C3=C1
CAS NO: 246256-50-8
Standard In CHIKey: GSK-3 inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C13H3ClN4O
M.Wt: 266.64
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/271/3/1320
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO
Storage: Store at -20℃
Purity: >98%
Chemical Name: 7-Chloro-9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile