Product Name: IPI-145 (INK1197)
Subtitle: PI3K-δ/PI3K-γ inhibitor
Biological Activity: Biological Activity of IPI-145 (INK1197)Description IPI-145 is an orally bioavailable and highly selective inhibitor of PI3K-δ and PI3K-γ with IC50 values of 0.36 nM and 19.6 nM, respectively. Targets PI3K-δ PI3K-γ IC50 0.36 nM 19.6
SMLES: C[C@@H](c1cc2cccc(c2c(=O)n1c3ccccc3)Cl)Nc4c5c([nH]cn5)ncn4
CAS NO: 1004316-88-4
Standard In CHIKey: HBV inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C22H17ClN6O
M.Wt: 416.86
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/257/1/382
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: duvelisib