Product Name: JLK 6
Subtitle: γ-secretase inhibitor
Biological Activity: Biological Activity of JLK 6Inhibitor of γ-secretase that selectively inhibits βAPP cleavage without affecting other γ-secretase-mediated pathways. Prevents recovery of Aβ40 and Aβ42 from HEK293 cell overexpressing wild-type or Swedish-mutated
SMLES: COC1=C(Cl)C2=CC=C(N)C=C2C(O1)=O
CAS NO: 161552-03-0
Standard In CHIKey: Sodium Channel inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C10H8ClNO3
M.Wt: 225.63
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/271/2/1096
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 25 mM in ethanol
Storage: Store at RT
Purity: >98%
Chemical Name: 7-Amino-4-chloro-3-methoxy-1H-2-benzopyran