Product Name: JNJ 10191584 maleate
Subtitle:
Biological Activity: Biological Activity of JNJ 10191584 maleateHighly selective histamine H4 receptor silent antagonist; binds with high affinity to the human H4 receptor (Ki = 26 nM). > 540-fold selective over the H3 receptor (Ki = 14.1 μM). Inhibits mast cell and eos
SMLES: ClC1=CC=C2N=C(C(N3CCN(C)CC3)=O)NC2=C1.OC(/C=C/C(O)=O)=O
CAS NO: 1227-61-8
Standard In CHIKey: ADC Linker inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C13H15ClN4O.C4H4O4
M.Wt: 394.81
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/270/2/713
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 50 mM in DMSO
Storage: Desiccate at RT
Purity: >98%
Chemical Name: 1-[(5-Chloro-1H-benzimidazol-2-yl)carbonyl]-4-methylpiperazine maleate