Product Name: JNJ 16259685
Subtitle:
Biological Activity: Biological Activity of JNJ 16259685Sub-nanomolar potent, non-competitive mGlu1 antagonist (Ki = 0.34 nM). Inhibits glutamate-induced Ca2+ response at the human mGlu1 receptor with an IC50 value of 0.55 nM. Selective over mGlu5 (> 400-fold) and displays
SMLES: O=C(C1=CC=C2N=C3OCCCC3=CC2=C1)[C@@H](CC4)CC[C@@H]4OC
CAS NO: 130-40-5
Standard In CHIKey: HCV inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C20H23NO3
M.Wt: 325.41
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/270/2/639
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in ethanol and to 25 mM in DMSO
Storage: Store at +4℃
Purity: >98%
Chemical Name: (3,4-Dihydro-2H-pyrano[2,3-b]quinolin-7-yl)-(cis-4-methoxycyclohexyl)-methanone