Product Name: JNJ 303
Subtitle: potent blocker of the slow component of delayed rectifier potassium current (IKs)
Biological Activity: Biological Activity of JNJ 303Potent IKs blocker (IC50 = 64 nM). Displays no effects on other cardiac channels; IC50 values are 3.3, >10, 11.1 and 12.6 μM for INa, ICa, Ito and IKr currents respectively. Prolongs QT and causes unprovoked torsades
SMLES: ClC1=CC=C(C=C1)OC(C)(C)C(N[C@@H]([C@@H]2C3)[C@H](C4)C[C@@]3(C[C@H]4C2)NS(=O)(C)=O)=O
CAS NO: 1361030-48-9
Standard In CHIKey: Casein Kinase inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C21H29ClN2O4S
M.Wt: 440.98
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/274/2/783
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 25 mM in DMSO
Storage: Store at +4℃
Purity: >98%
Chemical Name: 2-(4-Chlorophenoxy)-2-methyl-N-[5-[(methylsulfonyl)amino]tricyclo[3.3.1.13,7]dec-2-yl]-propanamide