Product Name: KM 11060
Subtitle:
Biological Activity: Biological Activity of KM 11060Corrects F508del-CFTR trafficking; increases the amount of functional CFTR at the plasma membrane (~75%). Shown to inhibit PDE5 activity.
SMLES: ClC1=CC=C2C(N3CCN(CC3)S(=O)(C(C=C4)=CC=C4Cl)=O)=CC=NC2=C1
CAS NO: 1453848-26-4
Standard In CHIKey: Alkaloid inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C19H17Cl2N3O2S
M.Wt: 422.33
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/274/1/562
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 10 mM in ethanol
Storage: Store at RT
Purity: >98%
Chemical Name: 7-Chloro-4-[4-[4-chlorophenyl)sulfonyl]-1-piperazinyl]quinoline