Product Name: LY 367385
Subtitle: mGlu1a receptor antagonist
Biological Activity: Biological Activity of LY 367385A selective mGlu1a receptor antagonist, with an IC50 value of 8.8 μM for blockade of quisqualate-induced phosphoinositide hydrolysis vs. > 100 μM for mGlu5a, and negligible action on group II and III receptors. Als
SMLES: OC([C@H](C1=CC=C(C(O)=O)C=C1C)N)=O
CAS NO: 134-63-4
Standard In CHIKey: GPR119 inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C10H11NO4
M.Wt: 209.2
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/270/1/269
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in 1.1eq. NaOH
Storage: Desiccate at RT
Purity: >98%
Chemical Name: (S)-(+)-α-Amino-4-carboxy-2-methylbenzeneacetic acid