Product Name: MG-132
Subtitle: Proteasome inhibitor, Cell permeable, reversible
Biological Activity: Biological Activity of MG-132Potent cell-permeable inhibitor of proteasome (IC50 = 100 nM) and calpain (IC50 = 1.2 μM). Inhibits TNF-α-induced NF-κB activation and IκBα degradation. Induces neurite outgrowth in PC12 cells and ha
SMLES: CC(C)C[C@@H](C=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1
CAS NO: 1300031-52-0
Standard In CHIKey: TZYWCYJVHRLUCT-UVKLAMSESA-NYAP inhibitors
Standard InChI: InChI=1S/C26H41N3O5/c1-17(2)12-21(15-30)27-24(31)22(13-18(3)4)28-25(32)23(14-19(5)6)29-26(33)34-16-20-10-8-7-9-11-20/h7-11,15,17-19,21-23H,12-14,16H2,1-6H3,(H,27,31)(H,28,32)(H,29,33)/t21-,22?,23?/m0/s1
Typrof Compound:
Appearance:
Formula: C26H41N3O5
M.Wt: 475.6
General Tips: for obtaining a higher concentration: Please warm the tube at 37 °C for 10 minutes and/or shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.PubMed ID:http://jpet.aspetjournals.org/content/259/3/947
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in ethanol and to 100 mM in DMSO
Storage: Store at -20℃
Purity: >98%
Chemical Name: