Product Name: MK-8745
Subtitle: Aurora A inhibitor,potent and selective
Biological Activity: Biological Activity of MK-8745Description MK-8745 is a potent and selective inhibitor of Aurora A with an IC50 value of 0.6 nM. Targets Aurora A IC50 0.6 nM
SMLES: ClC1=C(F)C(C(N2CCN(CC3=NC(NC4=NC=CS4)=CC=C3)CC2)=O)=CC=C1
CAS NO: 1035270-39-3
Standard In CHIKey: Ser_Thr Protease inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C20H19ClFN5OS
M.Wt: 431.91
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/252/1/428
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: (3-chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone