Product Name: MKT 077
Subtitle:
Biological Activity: Biological Activity of MKT 077Occupies mortalin-2 (mot-2), a member of the Hsp70 family, at its p53 binding site and enables p53 translocation to the nucleus. Selectively cytotoxic; causes growth arrest of cancer cells in culture. Also inhibits telomerase
SMLES: O=C1N(CC)/C(S/C1=C2SC3=CC=CC=C3N2C)=C/C4=CC=CC=[N+]4CC.[Cl-]
CAS NO: 124387-19-5
Standard In CHIKey: VSKYOTRJSLYFHX-UXJRWBAGSA-MMELK inhibitors
Standard InChI: InChI=1S/C21H22N3OS2.ClH/c1-4-23-13-9-8-10-15(23)14-18-24(5-2)20(25)19(27-18)21-22(3)16-11-6-7-12-17(16)26-21;/h6-14H,4-5H2,1-3H3;1H/q+1;/p-1/b21-19+;
Typrof Compound:
Appearance:
Formula: C21H22ClN3OS2
M.Wt: 432
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/271/3/1327
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 50 mM in water and to 50 mM in DMSO
Storage: Store at +4℃
Purity: >98%
Chemical Name: 1-Ethyl-2-[[3-ethyl-5-(3-methyl-2(3H)-benzothiazolylidene)-4-oxo-2-thiazolidinylidene]methyl]-pyridinium chloride