Product Name: ML133 HCl
Subtitle: Potassium channel inhibitor for Kir2.1
Biological Activity: Biological Activity of ML133 HClSelective blocker of inwardly rectifying Kir2 potassium channels (IC50 values are 1.8, 2.8, 2.9 and 4.0 μM at pH 7.4 for mKir2.1, hKir2.6, hKir2.2 and hKir2.3 respectively). Exhibits no effect on rKir1.1 (IC50 > 30
SMLES: COC1=CC=C(C=C1)CNCC2=CC=CC3=CC=CC=C32.Cl
CAS NO: 68406-26-8
Standard In CHIKey: Cell_Cycle/DNA_Damage_Compound_Library inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C19H19NO.HCl
M.Wt: 313.82
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/272/1/242
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 20 mM in water with gentle warming
Storage: Store at +4℃
Purity: >98%
Chemical Name: N-[(4-Methoxyphenyl)methyl]-1-naphthalenemethanamine hydrochloride