Product Name: Motesanib
Subtitle: Inhibitor of Flk-1/Flt-4/PDGFR-/c-Kit
Biological Activity: Biological Activity of MotesanibDescription Motesanib is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50 values of 2 nM, 3 nM and 6 nM, respectively. Targets VEGFR1 VEGFR2 VEGFR3 IC50 2 nM 3 nM 6 nM
SMLES: CC1(CNC2=C1C=CC(=C2)NC(=O)C3=C(N=CC=C3)NCC4=CC=NC=C4)C
CAS NO: 648450-29-7
Standard In CHIKey: RAHBGWKEPAQNFF-UHFFFAOYSA-NElastase inhibitors
Standard InChI: InChI=1S/C22H23N5O/c1-22(2)14-26-19-12-16(5-6-18(19)22)27-21(28)17-4-3-9-24-20(17)25-13-15-7-10-23-11-8-15/h3-12,26H,13-14H2,1-2H3,(H,24,25)(H,27,28)
Typrof Compound:
Appearance:
Formula: C22H23N5O
M.Wt: 373.46
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/259/2/595
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO
Storage:
Purity: >98%
Chemical Name: N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)pyridine-3-carboxamide