Product Name: NU7441 (KU-57788)
Subtitle: DNA-PK inhibitor
Biological Activity: Biological Activity of NU7441 (KU-57788)Potent and selective DNA-PK inhibitor (IC50 = 14 nM). Selective for DNA-PK over a range of kinases including mTOR, PI 3-K, ATM and ATR. Potentiates the effects of doxorubicin and etoposide in vitro and etoposide in
SMLES: C1COCCN1C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC5=C4SC6=CC=CC=C56
CAS NO: 1439399-58-2
Standard In CHIKey: Myosin inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C25H19NO3S
M.Wt: 413.49
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/257/2/812
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 5 mM in DMSO with gentle warming
Storage: Store at +4℃
Purity: >98%
Chemical Name: 8-(4-Dibenzothienyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one