Product Name: Nintedanib (BIBF 1120)
Subtitle: VEGFR/PDGFR/FGFR inhibitor
Biological Activity: Biological Activity of Nintedanib (BIBF 1120)Description Nintedanib (BIBF 1120) is a potent inhibitor of triple angiokinase for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively. Targ
SMLES: CN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)NC(=C3C4=C(C=C(C=C4)C(=O)OC)NC3=O)C5=CC=CC=C5
CAS NO: 65096-46-0
Standard In CHIKey: GPR139 inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C31H33N5O4
M.Wt: 539.62
General Tips: for obtaining a higher concentration: Please warm the tube at 37 °C for 10 minutes and/or shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.PubMed ID:http://jpet.aspetjournals.org/content/274/3/1387
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO
Storage:
Purity: >98%
Chemical Name: methyl (3Z)-3-[[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]anilino]-phenylmethylidene]-2-oxo-1H-indole-6-carboxylate