Product Name: PCI-34051
Subtitle: HDAC8 inhibitor,potent and selective
Biological Activity: Biological Activity of PCI-34051Potent and selective histone deacetylase 8 (HDAC8) inhibitor (IC50 = 10 nM). Displays >200 fold selectivity over HDAC isoforms 1, 2, 3, 6 and 10. Induces apoptosis in cell lines derived from T cell lymphomas or leukemi
SMLES: COC1=CC=C(C=C1)CN2C=CC3=C2C=C(C=C3)C(=O)NO
CAS NO: 1173699-31-4
Standard In CHIKey: TGF-beta_Smad inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C17H16N2O3
M.Wt: 296.32
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/252/2/845
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 20 mM in 1eq. NaOH
Storage: Store at -20℃
Purity: >98%
Chemical Name: N-Hydroxy-1-[(4-methoxyphenyl)methyl]-1H-indole-6-carboxamide