Product Name: PD 118057
Subtitle:
Biological Activity: Biological Activity of PD 118057Human ether-a-go-go (hERG) KV11.1 potassium channel activator. Displays no major effect on INa, ICa/L, IK1 and IKs currents. Causes resting membrane hyperpolarization and decreases action potential duration in rat myocytes
SMLES: ClC1=CC(CCC(C=C2)=CC=C2NC3=CC=CC=C3C(O)=O)=CC=C1Cl
CAS NO: 1415-73-2
Standard In CHIKey: Neuronal_Signaling_Compound_Library inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C21H17Cl2NO2
M.Wt: 386.27
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/274/1/437
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 20 mM in ethanol
Storage: Store at -20℃
Purity: >98%
Chemical Name: 2-[[4-[2-(3,4-Dichlorophenyl)ethyl]phenyl]amino]benzoic acid