Product Name: PG 01
Subtitle:
Biological Activity: Biological Activity of PG 01Cystic fibrosis transmembrane conductance regulator (CFTR) potentiator. Corrects gating defects of CFTR mutants such as ΔF508 (Ka = 0.3 μM), E193K and G970R (Kd values are 0.22 μM and 0.45 μM respectively).
SMLES: O=C(CC1=CNC2=CC=CC=C12)N(C)[C@H](C(NC3=CC=C(C=C3)C(C)C)=O)C4=CC=CC=C4
CAS NO: 85175-67-3
Standard In CHIKey: PQAYCXMQTUEDRD-UHFFFAOYSA-NDNA Stain inhibitors
Standard InChI: InChI=1S/C28H29N3O2/c1-19(2)20-13-15-23(16-14-20)30-28(33)27(21-9-5-4-6-10-21)31(3)26(32)17-22-18-29-25-12-8-7-11-24(22)25/h4-16,18-19,27,29H,17H2,1-3H3,(H,30,33)
Typrof Compound:
Appearance:
Formula: C28H29N3O2
M.Wt: 439.55
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/274/2/820
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO
Storage: Store at -20℃
Purity: >98%
Chemical Name: N-Methyl-N-[2-[[4-(1-Methylethyl)phenyl]amino]-2-1H-indole-3-acetamide