Product Name: PP 1
Subtitle: Src family tyrosine kinase inhibitor
Biological Activity: Biological Activity of PP 1Potent inhibitor of Src-family tyrosine kinases. Inhibits p56lck and p59fynT (IC50 values are 5 and 6 nM respectively). Displays > 8000-fold selectivity over ZAP-70 and JAK2. Also moderately inhibits p38, CSK, PDGF receptors,
SMLES: CC1=CC=C(C=C1)C2=NN(C3=C2C(=NC=N3)N)C(C)(C)C
CAS NO: 254109-22-3
Standard In CHIKey: Glucocorticoid Receptor inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C16H19N5
M.Wt: 281.36
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/274/3/1338
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 10 mM in DMSO and to 10 mM in ethanol
Storage: Desiccate at +4℃
Purity: >98%
Chemical Name: 1-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine