Product Name: PQ 401
Subtitle: IGF1R inhibitor,potent and cell-permeable
Biological Activity: Biological Activity of PQ 401Insulin-like growth factor receptor (IGF1R) inhibitor. Suppresses IGF-stimulated IGF-IR autophosphorylation with an IC50 value of 12 μM. Inhibits growth of MCF-7 breast cancer cells in vitro and in vivo.
SMLES: Cc1cc(c2ccccc2n1)NC(=O)Nc3cc(ccc3OC)Cl
CAS NO: 1035270-39-3
Standard In CHIKey: STING inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C18H16ClN3O2
M.Wt: 341.79
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/259/1/205
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 50 mM in DMSO and to 25 mM in ethanol
Storage: Store at +4℃
Purity: >98%
Chemical Name: N-(5-Chloro-2-methoxyphenyl)-N-(2-methyl-4-quinolinyl)urea