Product Name: Plinabulin (NPI-2358)
Subtitle: vascular disrupting agent
Biological Activity: Biological Activity of Plinabulin (NPI-2358)Description Plinabulin (NPI-2358), a vascular disrupting agent (VDA), is an inhibitor of tubulin-depolymerizing with IC50 of 9.8~18 nM in tumor cells. Targets Tubulin IC50 9.8 nM-18 nM
SMLES: CC(C)(C)C1=C(N=CN1)C=C2C(=O)NC(=CC3=CC=CC=C3)C(=O)N2
CAS NO: 1338806-73-7
Standard In CHIKey: Protease-Activated Receptor PAR) inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C19H20N4O2
M.Wt: 336.39
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/251/2/750
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: (3Z,6Z)-3-benzylidene-6-[(5-tert-butyl-1H-imidazol-4-yl)methylidene]piperazine-2,5-dione