Product Name: QS 11
Subtitle: Wnt synergistic agonist
Biological Activity: Biological Activity of QS 11GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling pathway to upregulate β-catenin nuclear translocation. Also reduces
SMLES: OC[C@H](CC1=CC=CC=C1)NC2=NC(OC3=CC=C4CCCC4=C3)=NC5=C2N=CN5CC6=CC=C(C7=CC=CC=C7)C=C6
CAS NO: 1415925-18-6
Standard In CHIKey: Itk inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C36H33N5O2
M.Wt: 567.68
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/259/3/1271
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage: Store at +4℃
Purity: >98%
Chemical Name: (2S)-2-[2-(Indan-5-yloxy)-9-(1,1-biphenyl-4-yl)methyl)-9H-purin-6-ylamino]-3-phenyl-propan-1-ol