Product Name: R406 (free base)
Subtitle: Syk inhibitor
Biological Activity: Biological Activity of R406 (free base)Description R406 (free base) is a potent inhibitor of Syk with IC50 of 41 nM. Targets Syk IC50 41 nM
SMLES: CC1(C(=O)NC2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)C
CAS NO: 1629267-75-9
Standard In CHIKey: Endothelin Receptor inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C22H23FN6O5
M.Wt: 470.4
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/274/3/1305
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one